Had evidence of
chronic organ damage at autopsy
had chronic organ damage
previously noted in their clinical histories
(n=306; autopsy study)
Chronic organ damage, which could be a result of HbS polymerization and its effects—hemolysis,anemia, and vaso-occlusion—is responsible for the morbidity and mortality of most patients with SCD. However, it can often go unrecognized.6,7,9
There is an ongoing need for improved management of patients with SCD and related organ damage.10
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